WARNINGS
To achieve effective parasite control, treatment should be based on the results of the parasitological examination of feces. Resistance of parasites to a particular class of anthelmintics may develop due to frequent and repeated use of an anthelmintic from the same class. Special precautions for safe use in target species: it is good practice, during deworming, to provide animals with lighter meals than usual. It is preferable to administer the drug on an empty stomach. With the administration of the veterinary medicinal product as indicated, the disappearance of adult parasites is achieved; to eliminate larval forms of Ancylostoma and Ascaris, it is necessary to repeat the complete treatment after 60 days for Ascaris infestations and after 18 days for Ancylostoma infestations, from the end of the first treatment. The elimination of parasites begins with the first administration, and the disappearance of eggs usually occurs within about ten days from the last administration. Therefore, the fecal examination for control should be performed after the aforementioned period of time. During treatment and even afterwards, it is necessary to carry out appropriate disinfestation operations in kennels or breeding facilities to avoid reinfestations. Furthermore, it is advisable to chemically denature the feces expelled by treated subjects to destroy any live parasites emitted and thus interrupt the continuation of the parasitic cycle. Special precautions to be taken by the person administering the veterinary medicinal product to animals: individuals with known hypersensitivity to Mebendazole should administer the veterinary medicinal product with caution. Special precautions for environmental protection: not applicable. Special restrictions on use and special conditions for use, including restrictions on the use of antimicrobial and parasitic veterinary medicines to limit the risk of resistance development: not applicable. Administration of excessive doses causes vomiting above 500 mg/kg body weight of active ingredient in dogs and above 300 mg/kg body weight of active ingredient in cats. Incompatibility: not applicable.
PHARMACOTHERAPEUTIC CATEGORY
Anthelmintics.
STORAGE
This veterinary medicinal product does not require any special storage temperature. After each use, close the bottle to protect the medicine from light and moisture. Store any remaining tablet fractions in the original bottle, closed with its own cap, and use within 5 days. Shelf life of the veterinary medicinal product packaged for sale: 5 years. Shelf life after first opening of the primary packaging: 6 months. Shelf life of tablet fractions: 5 days.
CONTRAINDICATIONS/ADVERSE EFFECTS
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
NAME
LEN 160 MG TABLETS FOR DOGS AND CATS
ADVERSE EFFECTS
Dog and cat. Very rare (< 1 animal/10,000 treated animals, including isolated reports): vomiting and diarrhea*, hepatotoxic reactions.*, mild and transient gastrointestinal disturbances. Reporting adverse events is important as it allows for continuous monitoring of the safety of a veterinary medicinal product. Reports should preferably be sent through a veterinarian to the marketing authorization holder or the national competent authority via the national reporting system. See the package leaflet for respective contacts.
PREGNANCY AND LACTATION
Use is not recommended during the first fifteen days of pregnancy. It can be used during lactation.
INDICATIONS
Anthelmintic for the treatment of parasitic infestations caused by Toxocara canis, Toxascaris leonina, Toxocara cati, Trichuris vulpis, Ancylostoma caninum, Ancylostoma braziliense, Uncinaria stenocephala, Dipylidium caninum, Taenia spp.
INTERACTIONS
None noted.
DOSAGE
For oral use. One tablet for every 8 kg body weight/day (equivalent to 20 mg of active substance/kg body weight/day) for infestations by Toxocara canis, Toxascaris leonina, Toxocara cati, Trichuris vulpis, Ancylostoma caninum, Ancylostoma braziliense, Uncinaria stenocephala (roundworms) even if mixed. One tablet for every 4 kg body weight/day (equivalent to 40 mg of active substance/kg body weight/day) for infestations by Dipylidium caninum and Taenia spp. (flatworms) and for mixed infestations of roundworms and flatworms. In both cases, the indicated dose should be administered for 3 consecutive days. Always round the animal’s weight to the next whole number. The tablet is easily divisible into four parts, each usable to treat 2 kg or 1 kg of animal depending on the type of parasitic infestation. Place the tablet on a flat surface with the side bearing the fracture lines facing up. Apply pressure with the thumb at the center of the tablet to achieve division into 4 quarters. If administration proves difficult, the tablets can be incorporated into a small amount of palatable food. During treatment, the animal does not lose either vitality or appetite. The drug is well tolerated even by very debilitated animals and those with concurrent diseases.
ACTIVE INGREDIENTS
One tablet contains the active substance: Mebendazole 160 mg. Excipients: rice starch, lactose monohydrate, sodium lauryl sulfate, magnesium stearate.
SAFETY IN TARGET SPECIES
Administration of excessive doses causes vomiting above 500 mg/kg body weight of active ingredient in dogs and above 300 mg/kg body weight of active ingredient in cats.
TARGET SPECIES
Dog and cat.
WITHDRAWAL TIME
Not applicable.
USE/ROUTE OF ADMINISTRATION
For oral use.